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Multicenter Trial of Naloxone in Alzheimer's Disease Ann Neurol 25:404-406, Henderson,V.W.,et al, 1989 See this aricle in Pubmed Article Abstract In a double-blind,placebo-controlled,crossover study of intravenously administered naloxone hydrochloride,54 subjects with clinically ascertained Alzheimer's disease tested at three university centers showed no significant improvement in neuropsychological performance after 1-mg or 10-mg doses;15 patients at 1 center were similarly unimproved after receiving 30 mg naloxone(single blind).Findings fail to support claims that naloxone monotherapy ameliorates cognitive impairments of Alzheimer's disease.

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(click to filter results - removes previous filter) Alzheimer's disease Alzheimer's disease,treatment of memory,disorder,treatment of naloxone treatment of neurologic disorder

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